iS CLINICAL Active Serum Review

blue jar with dropper, suggestion of skin serum

Clinical Active Serum has anti-aging, acne-fighting, and skin-brightening properties. This face serum smooths away fine lines and wrinkles while relaxing the skin's texture and has been clinically shown to deliver immediate and long-term results.

Unfortunately, your skin does not improve with age. As the years pass, wrinkles, brown patches, and general dullness often appear. Even if you're just a casual beauty fan, you've undoubtedly heard about serums recently, but you may not know. They seem to be in the same weird category of beauty products as toners—the one full of items that serious beauty enthusiasts can't live without, but the average person finds perplexing. Fortunately, it's not that difficult!

Many women are turning to a skin serum to help them overcome these issues. Serums are oil- or water-based liquids that you apply to your skin and absorb quickly. They usually come in little vials with a dropper, and only a few drops are needed to cover your entire face.

Unlike a lotion or cream, a skin serum is a highly concentrated formulation designed to absorb swiftly into the skin, offering an intensive dose of chemicals that can address common skin concerns. Serums are highly suggested for everyone concerned about the aging process. It's an excellent method to obtain more anti-aging benefits than your average moisturizer and sunscreen.

Why Should You Use a Serum?

Serums are made up of tiny molecules that penetrate rapidly and thoroughly, unlike creams and oils, including occlusive substances that can form a barrier on top of your skin. Serums are thin and fluid by nature, so you won't feel like you're wearing anything on your face.

In addition, there's a serum for everything, from dullness to fine wrinkles to dark spots. Most serums are non-comedogenic and are unlikely to clog pores or cause acne, especially if they are oil-free and silicone-free. Serums are more concentrated than other products' inactive components (like face creams). They will provide more significant and faster effects than most other topical skincare products because of their larger dose of active ingredients and ability to penetrate deeply.

Furthermore, they are easy to layer since they have a light texture (moisturizers, face oils, sunscreens, and foundations).

young beautiful woman with nose ring uses serum for face

Buying the Best Skin Serum

Are you having trouble finding the best serum for your skin type? Unfortunately, it is a difficult task, as numerous serums are available for various skin types. A water-based serum, for example, is better for oily skin, while a serum mixed with essential oils and a slightly rich texture is better for dry skin.

Face serums are essential in your face care routine because they address dullness, dark spotsblemishes, and sagging skin. Face serum will benefit you whether you have sensitive, dry, or oily skin. The amount of serum options available on the market is surprising, and they all promise fantastic, gorgeous skin. However, the simplest method to choose the best one for you is to consider the following factors.


When looking for the best skin serum, consider what kind of skin problem you're attempting to solve. For example, do you wish to reduce the appearance of tiny wrinkles around your mouth? Or get rid of those sunspots on your nose? Then, depending on your requirements, you should look for a serum that claims to do precisely what you require.


A face serum is more expensive than most other serums because the contents are concentrated and not diluted with fluff. This is why, when looking for the best skin serum, you should also consider the price. While more expensive serums tend to contain higher-quality components, cheaper options can perform miracles if you do your homework on your skin's demands ahead of time.

Also, once you've purchased your serum, it's a good idea to use it daily, as active ingredients tend to expire quickly.

Quality Ingredients

Ingredients are one of the most crucial factors to consider when buying a skin serum. Ensure the serum contains high-quality nutrients, including plant-based active compounds and anti-inflammatory substances.

Licorice and other plant-based active substances are natural skin brightening agents, making them ideal for dealing with uneven skin, scars, and sunspots. People with sensitive skin should use a serum with anti-inflammatory components like Aloe Vera, Arnica, and Zine. Such a serum improves the appearance of your skin and helps prevent inflammation, breakouts, and redness.

Skin Type

In addition, you should consider your skin type. If you have oily or acne-prone skin, search for a serum that contains salicylic acid, retinol, and rosehip seed oil. Try something with hyaluronic acid & Vitamin C for older and dry skin. Glycolic acid, which locks moisture and keeps skin renewed and regenerated, works well with normal skin.

iS CLINICAL Active Serum

The iS CLINICAL Active Serum is a fast-acting, long-lasting, and results-oriented solution that visibly evens skin tone, decreases the appearance of fine lines or wrinkles, and is ideal for blemish-prone skin.


Physicians describe the iS CLINICAL Active Serum as "amazing" and "phenomenal," with results usually appearing within a few days. A chilly tingling sensation will be felt upon application, indicating robust activity. This potent botanical serum is suitable for all skin types and ages, leaving the skin soft and supple.

The Active Serum has numerous advantages, including reducing fine lines and wrinkles and reducing uneven skin tone and blemishes. It also soothes and softens the skin while delivering immediate and long-term results.


The iS CLINICAL line of products is unique in that it exclusively contains high-quality, pure components. Their raw ingredients are pharmaceutical-grade and botanically based.

This botanical serum uses the healing power of nature to restore skin health. Sugar cane extract, a natural source of glycolic acid, is included. Glycolic acid is used to exfoliate the skin and remove dead skin cells and debris that clog the skin's surface. This enhances the appearance of the skin's complexion.

The lactic acid in this serum comes from bilberry extract, which moisturizes the skin. Salicylic acid, found in white willow bark extract, is one of the most effective acne treatments. Salicylic acid goes deep into the pores, cleaning them of blemish-causing debris and shrinking them. Arbutin and mushroom extract are also included in the serum, which aids in the reduction of hyperpigmentation. It is also paraben-free.

bilberries and bilberry extract powder

Serums for Different Skin Types

Following are the different skin types and what you should look for in a skin serum.

Dry Skin

Serums might feel like small miracles in a bottle for individuals with dry skin because of their extraordinary capacity to nourish skin's deeper layers. Consider a serum that contains hyaluronic acid and glycerin if you have dry skin. Hyaluronic acid draws and retains moisture in the skin and temporarily plumps fine wrinkles. Glycerin is a humectant, meaning that it can retain moisture.

Oily Skin

If you have oily skin, opt for a serum that helps to balance and manage your natural oils. Look for a serum that contains Vitamin B3 and Clary Sage. Vitamin B3 (also known as niacinamide) is an antioxidant that helps to regulate oils that clog pores. Clary sage is a fragrant Mediterranean herb that works as a natural cleanser. It also aids in regulating natural oils, making it ideal for oily skin!

Closeup of beautiful asian girl model with natural face makeup looking at oil absorbing tissue

Combination Skin

You want a serum that helps retain your natural glow and protects your skin from the environment because there's nothing special, you're targeting. Pink grapefruit with Ferulic acid makes the ideal serum for combination skin. Pink grapefruit is high in antioxidants & citric acid, which serves as a natural exfoliator; on the other hand, ferulic acid is a natural antioxidant that creates a compounding when paired with vitamins C and E antioxidant effect.

Uneven Skin

Face serums are a wonder because it's challenging to find a product that genuinely balances skin tone. However, vitamin C and licorice root are two components that can help with the condition. Vitamin C is a potent antioxidant that can help fade discoloration and even skin tone. When combined with vitamin E, Liquiritin, an antioxidant found in licorice root, can also aid with the look of uneven skin color.

Aging Skin and Wrinkles

Face serums are ideal for aged skin due to their high concentration. Organic Jojoba and Rosehip Oil are two components to seek if you want to decrease wrinkles and tighten your skin. Organic jojoba softens and conditions older skin because of being bio-identical to your skin's natural oil. It also serves as a weatherproof barrier. Rosehip oil is high in antioxidants like beta-carotene, which protect the skin. It also firms and tightens the skin, giving it a more youthful appearance.

Sensitive Skin

You're in for a treat if you have sensitive skin and have never tried a serum! Sensitive skin loves serums. Organic Aloe Vera and Chamomile are two substances that work particularly well for sensitive skin. Organic Aloe Vera hydrates and protects the skin; ideal for delicate skin. Chamomile is known for its soothing characteristics, which are particularly beneficial to the skin and offer a thin protective shield.

What Are Clinical Active Serums?

The iS CLINICAL Active Serum is designed to alter the short and long-term skin. It contains several potent botanicals that assist in reducing the appearance of wrinkles, removing blemishes, and brightening skin tone. In addition, the paraben-free product tingles and quickly smooths and hydrates tired skin when applied.

The active serum is the flagship and one of the most popular products of the iS CLINICAL line of skincare products. The active serum is a plant-based serum that helps decrease fine lines and wrinkles, enhance skin quality and texture, and reduce the frequency of pimples and acne.

Overall, it's meant to improve the quality of your skin and serve as a supplement to your current skincare regimen.

When it comes to facial accessories, the most outstanding facial products are frequently plant-based rather than synthetic-based, and active serum is one of them. It's a blend of unique plant-based components that help to improve the quality of your skin organically. These plant-based treatments help brighten the skin and complexion while also managing acne.

In as little as four weeks, most people will see a noticeable difference after utilizing this product daily. The active serum is best defined as an "anti-aging" product since, while it helps in various areas, its primary goal is to improve skin conditions.

You may notice an improvement in your complexion, a reduction in fine lines and wrinkles, breakouts, a fading of age or dark spots on your face, and improved skin (this varies from person to person).

Although most individuals will have no problems with this serum, some people may have irritation, redness, or dryness with daily use. However, this irritation does not mean you should stop using the product! Instead, you may need to reduce your serum usage to every other day until your body becomes "accustomed" to it.

Some people may notice minor tingling with everyday use, which is perfectly normal. This also does not mean that you should stop using the serum. It's well accepted because it's made up of plant-based product formulae.

3D rendering of serum and vitamin drop on skin cell

How Do Clinical Active Serums Benefit Your Skin?

Clinical Active Serum was created to address several issues, including:

Fine Lines and Wrinkles

Fine lines are one of the most common early symptoms of aging. Fine wrinkles around the eyes and other parts of the face may form when the skin begins to age. These shallow lines occur along your expression lines when you smile, laugh, or frown.

The breakdown of collagen and elastin in the skin causes fine lines and wrinkles. Collagen and elastin provide skin with support structure, allowing it to stay smooth and resilient. However, the skin loses its strength and suppleness as these fibers break down.

The Clinical Active Serum is a lightweight serum with a pH of 3.8, ideal for anti-aging and acne and hyperpigmented skin. It also aids in the breakdown of oil in clogged pores. As a result, the look of fine lines and wrinkles improves almost immediately.

Sun-Damaged Skin

Photoaging, photodamage, solar damage, and sun damage are all terms dermatologists use to describe the effects of the sun on the skin. When UV light strikes skin that hasn't been covered by sunscreen, it causes DNA alterations at the cellular level.

Acne-Prone Skin

Comedones and pimples are more likely to appear on blemish-prone skin. It is often oily and appears shiny. The sebaceous glands create more sebum in this skin type than in others.

Salicylic acid is an exfoliator, and the Polyporus Umbellatus mushroom is a lightener and antioxidant. The serum's effectiveness distinguishes it, as it works rapidly to eliminate post-acne blemishes, enhance skin texture and tighter pores, and ultra-smooth, dewy skin.


Hyperpigmentation is when certain parts of the skin are darker than others. Extra melanin causes brown, black, grey, red, or pink spots or patches. Although the areas are neither unpleasant nor irritating, they can make people uncomfortable.

Hyperpigmentation can be treated with Clinical Active Serums, as it has antioxidants or an active ingredient specially designed to reduce dark spots or hyperpigmentation.

Young Asian women having a skin problem with melasma and hyperpigmentation on her face

Fine Stretch Marks

Stretch marks are small lines that appear as the skin expands due to rapid growth or weight gain (like during puberty). When skin is overstretched, the regular creation of collagen, the primary protein that makes up skin tissue, is interrupted.

Clinical active serums aid with fine stretch marks and elevated scars by providing UV protection. This potent serum aims to anti-aging, whitening, and scar tissue reduction.

Poor Elasticity/Thin Skin

Elastosis is the loss of skin elasticity. As a result, Elastosis creates sagging, crinkled, or leathery skin. Solar Elastosis affects areas of the skin that are exposed to the sun. These body areas may appear more worn than others not exposed to the sun.

Anti-aging, anti-acne, and brightening properties are provided by iS CLINICAL Active Serum. This face serum, clinically proven to deliver both immediate and long-term results, smooths away fine lines and wrinkles while relaxing its texture, making it ideal for thin skin.

Final Thoughts

After cleansing, apply iS CLINICAL Active Serum on its own or as part of your regular skincare routine. On application, some people may experience a slight tingling sensation when using the serum; therefore, you may not enjoy the feeling if you have sensitive skin. You should also avoid using the serum near your eyes because it is powerful and could irritate them.

After three months of treatment, iS CLINICAL has highly positive before and after photographs showing substantial improvement in skin suffering from acne, hyperpigmentation, and fine lines and wrinkles. After cleansing at night, apply the serum and let it soak in for at least 10 minutes before using a night cream. You will always wake up with fresh, smooth, moisturized skin, and you should not experience any skin dryness due to the active components.

Was this article helpful?